Dallas Lab

Dallas Lab

Unraveling the biology of human and animal milk

We specialize in the following areas

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bioactive milk peptides

Bioactive milk peptides

Identifying novel bioactive protein fragments—peptides—in human and bovine milk

Identifying which milk peptides are present across the digestive tract (infants and adults)

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bioactive milk proteins

Bioactive milk proteins

Determining which milk proteins survive intact across digestion, enabling them to exert function throughout the gut

Improving protein preservation across milk processing

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improving preterm infant health

Improving preterm infant health

Assessing digestive deficiencies in preterm infants

Improving processing of human milk to enhance bioactivity

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improving adult health

Improving adult health

Assessing the survival of functional bovine milk proteins and peptides across adult digestion

Assessing the effect of bovine milk proteins and peptides on health (e.g., immune system, microbiome)

Improving processing of bovine milk components to enhance bioactivity

Our approach

Clinical studies

  • Collecting digestive fluids from infants and adults
  • Feeding studies

Digestion models

  • Static and dynamic simulated infant and adult digestion

Structural analysis

  • Peptidomics
  • proteomics
  • Glycopeptidomics
  • Enzyme-linked immunosorbent assays

Functional assays

  • Immunomodulatory assays (e.g., macrophage cell culture)
  • Intestinal cell culture
  • Antimicrobial assays

Updates and Good news

Recent publications

See more publications

2024

Sutantawong, S., Kim, B.J., Qu, Y., Dallas, D.C.  (2024)  Survival of intact bovine whey proteins across in vivo and simulated static in vitro models of the adult gastrointestinal tract  Food Chemistry  465(1)
Sutantawong, S., Kim, B.J., Kuhfeld, R.F., Qu, Y., Dallas, D.C.  (2024)  Release of bioactive peptides from whey proteins across digestion in adult humans and a static in vitro digestion model  Journal of Functional Foods  122
Haas, J., Kim, B.J., Atamer, Z., Wu, C., Dallas, D.C.  (2024)  Effects of spray drying and freeze drying on the protein profile of whey protein concentrate  Journal of Food Science  
Biondi Ryan, M., Kim, B., Qu, Y., Dallas, D.C.  (2024)  Detection of milk-derived peptides in human blood post-digestion, using LC-MS/MS  Journal of Functional Foods  122
Haas, J., Kim, B.J., Atamer, Z., Wu, C., Dallas, D.C.  (2024)  Effects of high temperature short time (HTST) pasteurization on milk and whey during commercial whey protein concentrate production  Journal of Dairy Science