Research interests are in the area of antioxidants and gene expression and dietary chemoprevention strategies. I am currently interested in understanding the role of the antioxidant nutrients such as zinc in maintaining DNA integrity and cancer development. Specifically, I am concerned with the effects of zinc status on DNA damage, DNA repair and stress-response signal pathways. We are also becoming interested in the effects of zinc on the immune system, especially as we age. A large proportion of population does not eat enough zinc, especially the elderly, and hence may be at increased risk for cancer and other disorders. Another major focus in the lab is dietary approaches for prostate cancer prevention. We are investigating the molecular mechanisms by which foods like soy, tea and cruciferous vegetables may protect against prostate cancer.