Gut Health Research

Gut Health Research

Moore Family Center

Discover gut health research at The Moore Family Center, where our experts explore the intricate connections between foods and digestive health to pioneer preventive health strategies.

Effects of Human Milk Handling Practices on Peptide Release and Bioactivity in the Preterm Infant Intestine

Primary investigators

Dave Dallas, Brian Scottoline (Oregon Health & Sciences University), Yimin Chen (University of Idaho), Yanming Di (OSU)

Team members

Abdul Wazed, Bum Jin Kim, Atik Rahman, Rohit Kumar

Funder

National Institutes of Health

Description

Our long-term goal is to determine feeding practices for preterm infants that promote optimal ex utero development and growth. The overall objective of this proposal is to identify how common milk handling practices affect the release of gut health-promoting peptides within the preterm infant intestine. The positive impact of this research is that it will help determine optimal milk handling practices for preterm infants, and provide a pipeline for supplementation strategies for milk that will lead to improved bioactivity within the infant gut.

Can High Pressure Processing of Donor Milk Improve Lipid Absorption and Growth in Preterm Infants Compared with Holder Pasteurization?

Primary investigators

Dave Dallas, Brian Scottoline (OHSU), Yanming Di (OSU)

Team members

Bum Jin Kim, Caleb Mark, Molly Aloia

Funder

Gerber Foundation

Description

Our long-term goal is to optimize feeding practices for preterm infants to improve their health outcomes. Our overall objective is to determine the extent to which HPP-treated milk increases fat digestion and absorption, impacts growth and affects other clinical outcomes in infants compared with Holder pasteurized human donor milk. The positive impact of this research is that it will guide future human milk processing to improve infant health outcomes.