College of Health

C. D. Green, Jump, D. B., and L Olson, K., “Elevated insulin secretion from liver X receptor-activated pancreatic beta-cells involves increased de novo lipid synthesis and triacylglyceride turnover.”, Endocrinology, vol. 150, no. 6, pp. 2637-45, 2009.

D. B. Jump, “Mammalian fatty acid elongases.”, Methods in molecular biology (Clifton, N.J.), vol. 579, pp. 375-89, 2009.

S. Tripathy, Torres-Gonzalez, M., and Jump, D. B., “Elevated hepatic fatty acid elongase-5 activity corrects dietary fat-induced hyperglycemia in obese C57BL/6J mice.”, Journal of lipid research, vol. 51, no. 9, pp. 2642-54, 2010.

P. J. Menagh, Turner, R. T., Jump, D. B., Wong, C. P., Lowry, M. B., Yakar, S., JRosen, C., and Iwaniec, U. T., “Growth hormone regulates the balance between bone formation and bone marrow adiposity.”, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol. 25, no. 4, pp. 757-68, 2010.

M. Tikhonenko, Lydic, T. A., Wang, Y., Chen, W., Opreanu, M., Sochacki, A., McSorley, K. M., Renis, R. L., Kern, T., Jump, D. B., Reid, G. E., and Busik, J. V., “Remodeling of retinal Fatty acids in an animal model of diabetes: a decrease in long-chain polyunsaturated fatty acids is associated with a decrease in fatty acid elongases Elovl2 and Elovl4.”, Diabetes, vol. 59, no. 1, pp. 219-27, 2010.

C. D. Green, Ozguden-Akkoc, C. G., Wang, Y., Jump, D. B., and L Olson, K., “Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species.”, Journal of lipid research, vol. 51, no. 7, pp. 1871-7, 2010.

D. B. Jump, “Fatty acid regulation of hepatic lipid metabolism.”, Current opinion in clinical nutrition and metabolic care, vol. 14, no. 2, pp. 115-20, 2011.

D. B. Jump, Torres-Gonzalez, M., and L Olson, K., “Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation.”, Biochemical pharmacology, vol. 81, no. 5, pp. 649-60, 2011.

K. M. Lebold, Jump, D. B., Miller, G. W., Wright, C. L., Labut, E. M., Barton, C. L., Tanguay, R. L., and Traber, M., “Vitamin E deficiency decreases long-chain PUFA in zebrafish (Danio rerio).”, The Journal of nutrition, vol. 141, no. 12, pp. 2113-8, 2011.

C. M. Depner, Torres-Gonzalez, M., Tripathy, S., Milne, G., and Jump, D. B., “Menhaden oil decreases high-fat diet-induced markers of hepatic damage, steatosis, inflammation, and fibrosis in obese Ldlr-/- mice.”, The Journal of nutrition, vol. 142, no. 8, pp. 1495-503, 2012.

D. B. Jump, Depner, C. M., and Tripathy, S., “Omega-3 fatty acid supplementation and cardiovascular disease.”, Journal of lipid research, vol. 53, no. 12, pp. 2525-45, 2012.

C. M. Depner, Philbrick, K. A., and Jump, D. B., “Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis.”, J Nutr, vol. 143, no. 3, pp. 315-23, 2013.

S. Tripathy and Jump, D. B., “Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice.”, Journal of lipid research, vol. 54, no. 1, pp. 71-84, 2013.

D. B. Jump, Tripathy, S., and Depner, C. M., “Fatty acid-regulated transcription factors in the liver.”, Annu Rev Nutr, vol. 33, pp. 249-69, 2013.

C. M. Depner, Traber, M., Bobe, G., Kensicki, E., Bohren, K. M., Milne, G., and Jump, D. B., “A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.”, PLoS One, vol. 8, no. 12, p. e83756, 2013.

K. M. Lebold, Kirkwood, J. S., Taylor, A. W., Choi, J., Barton, C. L., Miller, G. W., La Du, J., Jump, D. B., Stevens, J. Frederik, Tanguay, R. L., and Traber, M., “Novel liquid chromatography-mass spectrometry method shows that vitamin E deficiency depletes arachidonic and docosahexaenoic acids in zebrafish (Danio rerio) embryos.”, Redox biology, vol. 2, pp. 105-13, 2013.

R. F. Cooke, Cappellozza, B. I., Filho, T. A. Guarnier, Depner, C. M., Lytle, K. A., Jump, D. B., Bohnert, D. W., Cerri, R. L. A., and Vasconcelos, J. L. M., “Effects of calcium salts of soybean oil on factors that influence pregnancy establishment in Bos indicus beef cows.”, J Anim Sci, vol. 92, no. 5, pp. 2239-50, 2014.

S. Tripathy, Lytle, K. A., Stevens, R. D., Bain, J. R., Newgard, C. B., Greenberg, A. S., Huang, L. - S., and Jump, D. B., “Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice.”, Journal of lipid research, vol. 55, no. 7, pp. 1448-1464, 2014.

K. A. Lytle, Depner, C. M., Wong, C. P., and Jump, D. B., “Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis in Ldlr-/- mice by targeting the TGFβ-Smad3 pathway.”, J Lipid Res, vol. 56, no. 10, pp. 1936-46, 2015.

B. I. Cappellozza, Cooke, R. F., Reis, M. M., Marques, R. S., Filho, T. A. Guarnier, Perry, G. A., Jump, D. B., Lytle, K. A., and Bohnert, D. W., “Effects of protein supplementation frequency on physiological responses associated with reproduction in beef cows.”, J Anim Sci, vol. 93, no. 1, pp. 386-94, 2015.

D. B. Jump, Depner, C. M., Tripathy, S., and Lytle, K. A., “Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer.”, Advances in nutrition (Bethesda, Md.), vol. 6, no. 6, pp. 694-702, 2015.

D. B. Jump, Depner, C. M., Tripathy, S., and Lytle, K. A., “Impact of dietary fat on the development of non-alcoholic fatty liver disease in Ldlr-/- mice.”, Proc Nutr Soc, vol. 75, no. 1, pp. 1-9, 2016.

K. A. Lytle and Jump, D. B., “Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible?”, PLoS One, vol. 11, no. 1, p. e0146942, 2016.

K. A. Lytle, Wong, C. P., and Jump, D. B., “Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice”, PLOS ONE, no. 4603715694913Suppl 12413624367446441413125105771810712858318382951Suppl 12224256130393, p. e0173376, 2017.

D. B. Jump, Lytle, K. A., Depner, C. M., and Tripathy, S., “Omega-3 polyunsaturated fatty acids as a treatment strategy for nonalcoholic fatty liver disease.”, Pharmacol Ther, vol. 181, pp. 108-125, 2018.