College of Public Health and Human Sciences

D. B. Jump, “Fatty acid regulation of hepatic lipid metabolism.”, Current opinion in clinical nutrition and metabolic care, vol. 14, no. 2, pp. 115-20, 2011.

D. B. Jump, Torres-Gonzalez, M., and L Olson, K., “Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation.”, Biochemical pharmacology, vol. 81, no. 5, pp. 649-60, 2011.

K. M. Lebold, Jump, D. B., Miller, G. W., Wright, C. L., Labut, E. M., Barton, C. L., Tanguay, R. L., and Traber, M., “Vitamin E deficiency decreases long-chain PUFA in zebrafish (Danio rerio).”, The Journal of nutrition, vol. 141, no. 12, pp. 2113-8, 2011.

S. Tripathy, Torres-Gonzalez, M., and Jump, D. B., “Elevated hepatic fatty acid elongase-5 activity corrects dietary fat-induced hyperglycemia in obese C57BL/6J mice.”, Journal of lipid research, vol. 51, no. 9, pp. 2642-54, 2010.

P. J. Menagh, Turner, R. T., Jump, D. B., Wong, C. P., Lowry, M. B., Yakar, S., JRosen, C., and Iwaniec, U. T., “Growth hormone regulates the balance between bone formation and bone marrow adiposity.”, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol. 25, no. 4, pp. 757-68, 2010.

M. Tikhonenko, Lydic, T. A., Wang, Y., Chen, W., Opreanu, M., Sochacki, A., McSorley, K. M., Renis, R. L., Kern, T., Jump, D. B., Reid, G. E., and Busik, J. V., “Remodeling of retinal Fatty acids in an animal model of diabetes: a decrease in long-chain polyunsaturated fatty acids is associated with a decrease in fatty acid elongases Elovl2 and Elovl4.”, Diabetes, vol. 59, no. 1, pp. 219-27, 2010.

C. D. Green, Ozguden-Akkoc, C. G., Wang, Y., Jump, D. B., and L Olson, K., “Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species.”, Journal of lipid research, vol. 51, no. 7, pp. 1871-7, 2010.

C. D. Green, Jump, D. B., and L Olson, K., “Elevated insulin secretion from liver X receptor-activated pancreatic beta-cells involves increased de novo lipid synthesis and triacylglyceride turnover.”, Endocrinology, vol. 150, no. 6, pp. 2637-45, 2009.

D. B. Jump, “Mammalian fatty acid elongases.”, Methods in molecular biology (Clifton, N.J.), vol. 579, pp. 375-89, 2009.

D. B. Jump, Botolin, D., Wang, Y., Xu, J., Demeure, O., and Christian, B., “Docosahexaenoic acid (DHA) and hepatic gene transcription.”, Chem Phys Lipids, vol. 153, no. 1, pp. 3-13, 2008.

Y. Wang, Torres-Gonzalez, M., Tripathy, S., Botolin, D., Christian, B., and Jump, D. B., “Elevated hepatic fatty acid elongase-5 activity affects multiple pathways controlling hepatic lipid and carbohydrate composition.”, J Lipid Res, vol. 49, no. 7, pp. 1538-52, 2008.

D. B. Jump, “N-3 polyunsaturated fatty acid regulation of hepatic gene transcription.”, Current opinion in lipidology, vol. 19, no. 3, pp. 242-7, 2008.

W. Chen, Jump, D. B., Esselman, W. J., and Busik, J. V., “Inhibition of cytokine signaling in human retinal endothelial cells through modification of caveolae/lipid rafts by docosahexaenoic acid.”, Investigative ophthalmology & visual science, vol. 48, no. 1, pp. 18-26, 2007.

D. Botolin, Wang, Y., Christian, B., and Jump, D. B., “Docosahexaneoic acid (22:6,n-3) regulates rat hepatocyte SREBP-1 nuclear abundance by Erk- and 26S proteasome-dependent pathways.”, J Lipid Res, vol. 47, no. 1, pp. 181-92, 2006.

Y. Wang, Botolin, D., Xu, J., Christian, B., Mitchell, E., Jayaprakasam, B., Nair, M. G., Nair, M., Peters, J. M., Peters, J. M., Busik, J. V., Busik, J., L Olson, K., and Jump, D. B., “Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity.”, Journal of lipid research, vol. 47, no. 9, pp. 2028-41, 2006.

J. Xu, Christian, B., and Jump, D. B., “Regulation of rat hepatic L-pyruvate kinase promoter composition and activity by glucose, n-3 polyunsaturated fatty acids, and peroxisome proliferator-activated receptor-alpha agonist.”, J Biol Chem, vol. 281, no. 27, pp. 18351-62, 2006.

D. B. Jump, Botolin, D., Wang, Y., Xu, J., Christian, B., and Demeure, O., “Fatty acid regulation of hepatic gene transcription.”, The Journal of nutrition, vol. 135, no. 11, pp. 2503-6, 2005.

D. R. Boverhof, Burgoon, L. D., Tashiro, C., Chittim, B., Harkema, J. R., Jump, D. B., and Zacharewski, T. R., “Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDD-Mediated hepatotoxicity.”, Toxicol Sci, vol. 85, no. 2, pp. 1048-63, 2005.

Y. Wang, Botolin, D., Christian, B., Busik, J., Xu, J., and Jump, D. B., “Tissue-specific, nutritional, and developmental regulation of rat fatty acid elongases.”, J Lipid Res, vol. 46, no. 4, pp. 706-15, 2005.

D. B. Jump, “Fatty acid regulation of gene transcription.”, Crit Rev Clin Lab Sci, vol. 41, no. 1, pp. 41-78, 2004.

W. Chen, Jump, D. B., Grant, M. B., Esselman, W. J., and Busik, J. V., “Dyslipidemia, but not hyperglycemia, induces inflammatory adhesion molecules in human retinal vascular endothelial cells.”, Invest Ophthalmol Vis Sci, vol. 44, no. 11, pp. 5016-22, 2003.

N. Parameswaran, Hall, C. S., Bomberger, J. M., Sparks, H. V., Jump, D. B., and Spielman, W. S., “Negative growth effects of ciglitazone on kidney interstitial fibroblasts: role of PPAR-gamma.”, Kidney Blood Press Res, vol. 26, no. 1, pp. 2-9, 2003.

A. Pawar, Botolin, D., Mangelsdorf, D. J., and Jump, D. B., “The role of liver X receptor-alpha in the fatty acid regulation of hepatic gene expression.”, J Biol Chem, vol. 278, no. 42, pp. 40736-43, 2003.

D. Botolin and Jump, D. B., “Selective proteolytic processing of rat hepatic sterol regulatory element binding protein-1 (SREBP-1) and SREBP-2 during postnatal development.”, J Biol Chem, vol. 278, no. 9, pp. 6959-62, 2003.

A. Pawar and Jump, D. B., “Unsaturated fatty acid regulation of peroxisome proliferator-activated receptor alpha activity in rat primary hepatocytes.”, J Biol Chem, vol. 278, no. 38, pp. 35931-9, 2003.