College of Public Health and Human Sciences

L. M. Beaver, Yu, T. - W., Sokolowski, E. I., Williams, D. E., Dashwood, R. H., and Ho, E., “3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.”, Toxicology and applied pharmacology, vol. 263, no. 3, pp. 345-51, 2012.

L. M. Beaver, Lӧhr, C. V., Clarke, J. D., Glasser, S. T., Watson, G. W., Wong, C. P., Zhang, Z., Williams, D. E., Dashwood, R. H., Shannon, J., Thuillier, P., and Ho, E., “Broccoli Sprouts Delay Prostate Cancer Formation and Decrease Prostate Cancer Severity with a Concurrent Decrease in HDAC3 Protein Expression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice.”, Curr Dev Nutr, vol. 2, no. 3, p. nzy002, 2018.

R. H. Dashwood and Ho, E., “Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.”, Nutrition reviews, vol. 66 Suppl 1, pp. S36-8, 2008.

E. Ho and Dashwood, R. H., “Dietary manipulation of histone structure and function.”, World review of nutrition and dietetics, vol. 101, pp. 95-102, 2010.

E. Ho, Clarke, J. D., and Dashwood, R. H., “Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention.”, The Journal of nutrition, vol. 139, no. 12, pp. 2393-6, 2009.

J. D. Clarke, Hsu, A., Yu, Z., Dashwood, R. H., and Ho, E., “Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells.”, Molecular nutrition & food research, 2011.

C. P. Wong, Hsu, A., Buchanan, A., Palomera-Sanchez, Z., Beaver, L. M., E Houseman, A., Williams, D. E., Dashwood, R. H., and Ho, E., “Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.”, PloS one, vol. 9, no. 1, p. e86787, 2014.

R. Wang, ,, Fischer, K., W Dashwood, M., Greenwood, J. A., Ho, E., Williams, D. E., Ashktorab, H., Dashwood, M. R., and Dashwood, R. H., “Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.”, International journal of cancer. Journal international du cancer, vol. 132, no. 5, pp. 1004-12, 2013.

L. M. Beaver, Kuintzle, R., Buchanan, A., Wiley, M. W., Glasser, S. T., Wong, C. P., Johnson, G. S., Chang, J. H., Löhr, C. V., Williams, D. E., Dashwood, R. H., Hendrix, D. A., and Ho, E., “Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer.”, J Nutr Biochem, vol. 42, pp. 72-83, 2017.

H. Nian, Delage, B., Ho, E., and Dashwood, R. H., “Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.”, Environmental and molecular mutagenesis, vol. 50, no. 3, pp. 213-21, 2009.

A. Hsu, Wong, C. P., Yu, Z., Williams, D. E., Dashwood, R. H., and Ho, E., “Promoter de-methylation of cyclin D2 by sulforaphane in prostate cancer cells.”, Clinical epigenetics, vol. 3, p. 3, 2011.

Z. Zhang, Garzotto, M., Davis, E. W., Mori, M., Stoller, W. A., Farris, P. E., Wong, C. P., Beaver, L. M., Thomas, G. V., Williams, D. E., Dashwood, R. H., Hendrix, D. A., Ho, E., and Shannon, J., “Sulforaphane Bioavailability and Chemopreventive Activity in Men Presenting for Biopsy of the Prostate Gland: A Randomized Controlled Trial.”, Nutr Cancer, vol. 72, no. 1, pp. 74-87, 2020.

L. Housley, Magana, A. Alcazar, Hsu, A., Beaver, L. M., Wong, C. P., Stevens, J. F., Choi, J., Jiang, Y., Bella, D., Williams, D. E., Maier, C. S., Shannon, J., Dashwood, R. H., and Ho, E., “Untargeted Metabolomic Screen Reveals Changes in Human Plasma Metabolite Profiles Following Consumption of Fresh Broccoli Sprouts.”, Mol Nutr Food Res, vol. 62, no. 19, p. e1700665, 2018.