TitleWhen Is Higher Neuroticism Protective Against Death? Findings From UK Biobank.
Publication TypeJournal Article
Year of Publication2017
AuthorsGale, CR, Cukic, I, Batty, GD, McIntosh, AM, Weiss, A, Deary, IJ
JournalPsychol Sci
Volume28
Issue9
Pagination1345-1357
Date Published09/2017
ISSN1467-9280
KeywordsAdult, Aged, Biological Specimen Banks, Cause of Death, Diagnostic Self Evaluation, Female, Health Status, Humans, Male, Middle Aged, Neuroticism, Pregnancy, United Kingdom
Abstract
 

We examined the association between neuroticism and mortality in a sample of 321,456 people from UK Biobank and explored the influence of self-rated health on this relationship. After adjustment for age and sex, a 1- SD increment in neuroticism was associated with a 6% increase in all-cause mortality (hazard ratio = 1.06, 95% confidence interval = [1.03, 1.09]). After adjustment for other covariates, and, in particular, self-rated health, higher neuroticism was associated with an 8% reduction in all-cause mortality (hazard ratio = 0.92, 95% confidence interval = [0.89, 0.95]), as well as with reductions in mortality from cancer, cardiovascular disease, and respiratory disease, but not external causes. Further analyses revealed that higher neuroticism was associated with lower mortality only in those people with fair or poor self-rated health, and that higher scores on a facet of neuroticism related to worry and vulnerability were associated with lower mortality. Research into associations between personality facets and mortality may elucidate mechanisms underlying neuroticism's covert protection against death.

DOI10.1177/0956797617709813
Alternate JournalPsychol Sci
PubMed ID28703694
PubMed Central IDPMC5595241
Grant ListMC_UU_12011/2 / / Medical Research Council / United Kingdom
MC_U147585819 / / Medical Research Council / United Kingdom
MR/K026992/1 / / Medical Research Council / United Kingdom
MC_UP_A620_1014 / / Medical Research Council / United Kingdom
MC_UU_12011/1 / / Medical Research Council / United Kingdom
/ / Wellcome Trust / United Kingdom
G0400491 / / Medical Research Council / United Kingdom
MC_U147585824 / / Medical Research Council / United Kingdom