TitleA survey of current Bayesian gene mapping methods.
Publication TypeJournal Article
Year of Publication2004
AuthorsMolitor, J, Marjoram, P, Conti, D, Thomas, D
JournalHuman genomics
Date Published2004 Aug
KeywordsMonte Carlo Method

Recently, there has been much interest in the use of Bayesian statistical methods for performing genetic analyses. Many of the computational difficulties previously associated with Bayesian analysis, such as multidimensional integration, can now be easily overcome using modern high-speed computers and Markov chain Monte Carlo (MCMC) methods. Much of this new technology has been used to perform gene mapping, especially through the use of multi-locus linkage disequilibrium techniques. This review attempts to summarise some of the currently available methods and the software available to implement these methods.