TitleSpecific effects of polyunsaturated fatty acids on gene expression.
Publication TypeJournal Article
Year of Publication1996
AuthorsBaillie, RA, Jump, DB, Clarke, SD
JournalCurr Opin Lipidol
Volume7
Issue1
Pagination53-5
Date Published1996 Feb
ISSN0957-9672
KeywordsAnimals, Dietary Fats, Unsaturated, Fatty Acids, Unsaturated, Gene Expression Regulation, Transcription Factors, Transcription, Genetic
Abstract

Dietary polyunsaturated fatty acids modulate the transcription of numerous proteins including several hepatic lipogenic enzymes. Several lines of evidence indicate that polyunsaturated fatty acids do not regulate the transcription of hepatic lipogenic genes via a peroxisomal proliferator-activated receptor, but the mechanism may involve transcription factors related to the carbohydrate response region.

DOI10.1097/00041433-199602000-00012
Alternate JournalCurr. Opin. Lipidol.
PubMed ID8925191
Grant ListR01 DK043220 / DK / NIDDK NIH HHS / United States
NIH-DK 43220 / DK / NIDDK NIH HHS / United States