TitleSirtuin 3: A major control point for obesity-related metabolic diseases?
Publication TypeJournal Article
Year of Publication2013
AuthorsNewsom, SA, Boyle, KE, Friedman, JE
JournalDrug Discov Today Dis Mech
Volume10
Issue1-2
Paginatione35-e40
Date Published06/2013
ISSN1740-6765
Abstract
 

Obesity and obesity-related complications are epidemic issues currently plaguing much of the developed world with increasing associated morbidity, mortality, and economic burden. In this brief review, we discuss emerging evidence and remaining questions regarding the possible role for mitochondrial sirtuin 3 as a therapeutic target for the treatment of obesity-related metabolic diseases.

DOI10.1016/j.ddmec.2013.04.001
Alternate JournalDrug Discov Today Dis Mech
PubMed ID23997790
PubMed Central IDPMC3756827
Grant ListT32 DK007658 / DK / NIDDK NIH HHS / United States
R01 DK062155 / DK / NIDDK NIH HHS / United States
P30 DK048520 / DK / NIDDK NIH HHS / United States
F32 DK095509 / DK / NIDDK NIH HHS / United States
K12 HD057022 / HD / NICHD NIH HHS / United States
R24 DK090964 / DK / NIDDK NIH HHS / United States