|Title||N-3 polyunsaturated fatty acid regulation of hepatic gene transcription.|
|Publication Type||Journal Article|
|Year of Publication||2008|
|Journal||Current opinion in lipidology|
|Date Published||2008 Jun|
The liver plays a central role in whole body lipid metabolism and adapts rapidly to changes in dietary fat composition. This adaption involves changes in the expression of genes involved in glycolysis, de-novo lipogenesis, fatty acid elongation, desaturation and oxidation. This review brings together metabolic and molecular studies that help explain n-3 (omega-3) polyunsaturated fatty acid regulation of hepatic gene transcription.