Title | N-3 polyunsaturated fatty acid regulation of hepatic gene transcription. |
Publication Type | Journal Article |
Year of Publication | 2008 |
Authors | Jump, DB |
Journal | Current opinion in lipidology |
Volume | 19 |
Issue | 3 |
Pagination | 242-7 |
Date Published | 2008 Jun |
Keywords | Genetic, Transcription |
Abstract | The liver plays a central role in whole body lipid metabolism and adapts rapidly to changes in dietary fat composition. This adaption involves changes in the expression of genes involved in glycolysis, de-novo lipogenesis, fatty acid elongation, desaturation and oxidation. This review brings together metabolic and molecular studies that help explain n-3 (omega-3) polyunsaturated fatty acid regulation of hepatic gene transcription. |