College of Public Health and Human Sciences

The purpose of this chapter is to give a very brief overview of the structure and function of vitamin E, then to focus on the best methods for its measurement for a variety of biological samples. Historically, vitamin E was considered difficult to measure because of its instability and its lipophilicity. These challenges have largely been overcome, and with modern technologies it is possible to detect femtomole (10–15 mol) quantities with accuracy and precision.