TitleLow-level methylmercury exposure through rice ingestion in a cohort of pregnant mothers in rural China.
Publication TypeJournal Article
Year of Publication2016
AuthorsHong, C, Yu, X, Liu, J, Cheng, Y, Rothenberg, SE
JournalEnviron Res
Volume150
Pagination519-27
Date Published10/2016
ISSN1096-0953
KeywordsAdult, Animals, China, Environmental Monitoring, Environmental Pollutants, Female, Fishes, Food Contamination, Hair, Humans, Maternal Exposure, Mercury, Methylmercury Compounds, Mothers, Oryza, Pregnancy, Rural Population, Shellfish, Young Adult
Abstract
 

BACKGROUND: Rice ingestion is an important dietary exposure pathway for methylmercury. There are few studies concerning prenatal methylmercury exposure through rice ingestion, yet the health risks are greatest to the developing fetus, and thus should be investigated.

OBJECTIVES: Our main objective was to quantify dietary methylmercury intake through rice and fish/shellfish ingestion among pregnant mothers living in southern China, where rice was a staple food and mercury contamination was considered minimal.

METHODS: A total of 398 mothers were recruited at parturition, who donated scalp hair and blood samples. Total mercury and/or methylmercury concentrations were measured in biomarkers, in rice samples from each participant's home, and in fish tissue purchased from local markets. Additional fish/shellfish mercury concentrations were obtained from a literature search. Dietary methylmercury intake during the third trimester was equivalent to the ingestion rate for rice (or fish/shellfish)×the respective methylmercury concentration.

RESULTS: Dietary methylmercury intake from both rice and fish/shellfish ingestion averaged 1.2±1.8µg/day (median=0.79µg/day, range=0-22µg/day), including on average 71% from rice ingestion (median: 87%, range: 0-100%), and 29% from fish/shellfish consumption (median 13%, range: 0-100%). Median concentrations of hair total mercury, hair methylmercury, and blood total mercury were 0.40µg/g (range: 0.08-1.7µg/g), 0.28µg/g (range: 0.01-1.4µg/g), and 1.2µg/L (range: 0.29-8.6µg/L), respectively, and all three biomarkers were positively correlated with dietary methylmercury intake through rice ingestion (Spearman's rho=0.18-0.21, p≤0.0005), although the correlations were weak. In contrast, biomarkers were not correlated with fish/shellfish methylmercury intake (Spearman's rho=0.04-0.08, p=0.11-0.46).

CONCLUSIONS: Among pregnant mothers living in rural inland China, rice ingestion contributed to prenatal methylmercury exposure, more so than fish/shellfish ingestion.

DOI10.1016/j.envres.2016.06.038
Alternate JournalEnviron. Res.
PubMed ID27423706
PubMed Central IDPMC5003649
Grant ListL30 ES023165 / ES / NIEHS NIH HHS / United States
R15 ES022409 / ES / NIEHS NIH HHS / United States