TitleInteraction between lipid availability,endurance exercise and insulin sensitivity.
Publication TypeJournal Article
Year of Publication2014
AuthorsNewsom, SA, Schenk, S
JournalMed Sport Sci
Date Published09/2014
KeywordsExercise, Fatty Acids, Humans, Inflammation, Insulin, Insulin Resistance, Lipid Metabolism, Muscle, Skeletal, Obesity, Physical Endurance, Signal Transduction, Triglycerides

This chapter summarizes current knowledge regarding the interaction between lipid availability, endurance exercise, and insulin sensitivity. We discuss the role of lipid availability as a key mediator of insulin resistance in obesity, the proposed cellular mechanisms underlying this relationship, recent studies demonstrating that acute exercise protects against lipid-induced insulin resistance, how fatty acid partitioning may contribute to this protective effect of endurance exercise and finally remaining questions and future directions in the field.

Alternate JournalMed Sport Sci
PubMed ID25226801