|Title||Genetic Markers of Extreme Human Longevity|
|Publication Type||Book Chapter|
|Year of Publication||2019|
|Authors||Sebastiani, P, Gurinovich, A, Bae, H, Perls, TT|
|Book Title||Healthy Ageing and Longevity|
|Pagination||137 - 153|
|Publisher||Springer International Publishing|
We review issues related to studying the genetics of extreme human longevity, including the definition of the phenotype, the choice of appropriate controls, the effect of population structure and assortative mating. We then discuss the important contributions to the genetics of extreme human longevity of the last few years that have arisen from genome-wide association studies and the work that is needed to discover additional longevity genes.