TitleGenetic Markers of Extreme Human Longevity
Publication TypeBook Chapter
Year of Publication2019
AuthorsSebastiani, P, Gurinovich, A, Bae, H, Perls, TT
EditorMoskalev, A
Book TitleHealthy Ageing and Longevity
Volume10
Pagination137 - 153
PublisherSpringer International Publishing
CityCham
ISBN Number978-3-030-24969-4
ISBN2199-9007
Abstract
 

We review issues related to studying the genetics of extreme human longevity, including the definition of the phenotype, the choice of appropriate controls, the effect of population structure and assortative mating. We then discuss the important contributions to the genetics of extreme human longevity of the last few years that have arisen from genome-wide association studies and the work that is needed to discover additional longevity genes.

DOI10.1007/978-3-030-24970-0_10