TitleEvidence for increased thermogenesis in female C57BL/6J mice housed aboard the international space stationAbstract
Publication TypeJournal Article
Year of Publication2021
AuthorsWong, CP, Iwaniec, UT, Turner, RT
Journalnpj Microgravity
Date Published06/2021

Sixteen-week-old female C57BL/6J mice were sacrificed aboard the International Space Station after 37 days of flight (RR-1 mission) and frozen carcasses returned to Earth. RNA was isolated from interscapular brown adipose tissue (BAT) and gonadal white adipose tissue (WAT). Spaceflight resulted in differential expression of genes in BAT consistent with increased non-shivering thermogenesis and differential expression of genes in WAT consistent with increased glucose uptake and metabolism, adipogenesis, and β-oxidation.

Short Titlenpj Microgravity