TitleDose-response effects of intermittent PTH on cancellous bone in hindlimb unloaded rats.
Publication TypeJournal Article
Year of Publication2007
AuthorsTurner, RT, Evans, GL, Lotinun, S, Lapke, PD, Iwaniec, UT, Morey-Holton, E
JournalJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Volume22
Issue1
Pagination64-71
Date Published2007 Jan
KeywordsWeight-Bearing
Abstract

HLU suppressed bone formation and resulted in bone loss in the tibial metaphysis of 6-month-old male rats. A human therapeutic dose of intermittent PTH (1 microg/kg/day) prevented the skeletal changes associated with HLU.
DOI10.1359/jbmr.061006