TitleDietary Nitrate and the Epidemiology of Cardiovascular Disease: Report From a National Heart, Lung, and Blood Institute Workshop.
Publication TypeJournal Article
Year of Publication2016
AuthorsAhluwalia, A, Gladwin, M, Coleman, GD, Hord, NG, Howard, G, Kim-Shapiro, DB, Lajous, M, Larsen, FJ, Lefer, DJ, McClure, LA, Nolan, BT, Pluta, R, Schechter, A, Wang, C-Y, Ward, MH, Harman, JL
JournalJ Am Heart Assoc
Volume5
Issue7
Date Published07/2016
ISSN2047-9980
KeywordsCardiovascular Diseases, Diet, Heart, Humans, National Heart, Lung, and Blood Institute (U.S.), Nitrates, Nitric Oxide, Nitrites, United States
Abstract
 

In view of continuing unanswered questions regarding the geographical and demographic distribution of cardiovascular disease, and recent discoveries about the effects of dietary nitrate on cardiovascular physiology, the National Heart, Lung, and Blood Institute (NHLBI) convened a workshop to identify approaches to address how best to incorporate the study of nitrate exposures into ongoing studies of cardiovascular epidemiology. The NHLBI invited speakers who had made recent contributions to the study of the functions of nitrate on the cardiovascular system, on the occurrence of nitrate in foods and drinking water, or who had expert knowledge of cardiovascular surveys with wide geographical variability and therefore the greatest potential variability in dietary and drinking water nitrate. Because of the history of research on the possible carcinogenicity of nitrite, an expert in this field was also invited. The following document is a synthesis of the material presented and discussed and of literature cited at the workshop. The workshop from which this article is derived was funded and convened by the NHLBI.

DOI10.1161/JAHA.116.003402
Alternate JournalJ Am Heart Assoc
PubMed ID27385425
PubMed Central IDPMC5015377
Grant ListP30 DK079626 / DK / NIDDK NIH HHS / United States
P30 GM106392 / GM / NIGMS NIH HHS / United States
R37 HL058091 / HL / NHLBI NIH HHS / United States