TitleChildhood Body Weight in Relation to Cause-Specific Mortality: 67 Year Follow-up of Participants in the 1947 Scottish Mental Survey.
Publication TypeJournal Article
Year of Publication2016
AuthorsBatty, GD, Calvin, CM, Brett, CE, Cukic, I, Deary, IJ
JournalMedicine (Baltimore)
Volume95
Issue6
Paginatione2263
Date Published02/2016
ISSN1536-5964
KeywordsAged, Body Mass Index, Cardiovascular Diseases, Cause of Death, Child, Female, Follow-Up Studies, Health Surveys, Humans, Male, Multivariate Analysis, Pediatric Obesity, Prospective Studies, Scotland
Abstract
 

The association between childhood body weight and adult health has been little-examined, and findings are inconsistent.In a representative sample of the Scottish nation (the Scottish Mental Survey of 1947), we examined the association between body mass index measured at 11 years of age and future cause-specific mortality by age 77 years. In this cohort study, a maximum of 67 years of follow-up of 3839 study members gave rise to 1568 deaths (758 from cardiovascular disease, 610 from any malignancy). After adjustment for covariates, there was some evidence of a relation between elevated childhood body mass index and rates of mortality ascribed to all-causes (hazard ratio per 1 SD increase in body mass index; 95% confidence interval: 1.09; 1.03, 1.14), cardiovascular disease (1.09; 1.01, 1.17), all cancers combined (1.12; 1.03, 1.21), smoking-related cancers (1.13; 1.03, 1.25), and breast cancer in women (1.27; 1.04, 1.56).In conclusion, we provide further observational evidence for the need for weight control measures in youth.

DOI10.1097/MD.0000000000002263
Alternate JournalMedicine (Baltimore)
PubMed ID26871765
PubMed Central IDPMC4753859
Grant ListG1001401 / / Medical Research Council / United Kingdom
MR/K026992/1 / / Medical Research Council / United Kingdom
/ / Biotechnology and Biological Sciences Research Council / United Kingdom
/ / Medical Research Council / United Kingdom