TitleAbiotrophia defectiva endocarditis and associated hemophagocytic syndrome--a first case report and review of the literature.
Publication TypeJournal Article
Year of Publication2008
AuthorsKiernan, TJ, O'Flaherty, N, Gilmore, R, Ho, E, Hickey, M, Tolan, M, Mulcahy, D, Moore, DP
JournalInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Date Published2008 Sep

In this manuscript we describe the first association in the literature between Abiotrophia defectiva endocarditis and the hemophagocytic syndrome. There are multiple important clinical points of information that must be highlighted from this case. A. defectiva is an aggressive organism with a high level of resistance to antibiotic pharmacotherapy with a high predilection for embolic complications and valvular destruction despite treatment with sensitive antibiotics. A. defectiva endocarditis has not been previously associated with the hemophagocytic syndrome. However, this case highlights the serious hematological complications that can occur with this dangerous bacterial pathogen.