Donald B. Jump, PhD

Professor


College Of Public Health and Human Sciences
107A Milam Hall (Office), 102 Milam Hall (Lab)
Corvallis, OR 97331

Email contact form

Office phone: 541-737-4007
Fax: 541-737-6914

School, program or other affiliation

  • School of Biological and Population Health Sciences
  • Center for Healthy Aging Research
  • Nutrition

Research Interests

The type and quantity of dietary fat we ingest impacts the onset and progression of chronic diseases, e.g., atherosclerosis, diabetes and obesity. Our studies focus on the impact dietary fat has on hepatic gene expression, i.e., diet-gene interactions. Over the years we have defined mechanisms by which specific dietary fats regulate gene transcription by controlling the activity or abundance of key transcription factors. These transcription factors target genes involved in hepatic carbohydrate and lipid metabolism. Since the liver plays a central role in whole body carbohydrate and lipid metabolism, our studies reveal how diet can modify liver function, which in turn affects our health and the onset of metabolic diseases.

Spotlight

Posters & Abstracts

  • Abstract: Dietary docosahexaenoic acid (DHA) halts progression of nonalcoholic steatohepatitis (NASH), but does not promote fibrosis remission in Ldlr-/- mice. (download abstract .pdf)
  • Poster: Dietary docosahexaenoic acid (DHA) attenuates nonalcoholic steatohepatitis (NASH) progression, but does not promote NASH remission in Ldlr-/- mice. (download poster .pdf)
  • Poster: Western diet induced nonalcoholic steatohepatitis (NASH) in Ldlr-/- mice is only partially resolved by two separate low-fat diet regimes. (download poster .pdf)

Long Vita

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PubMed research listing

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Publications